BDBM86748 CAS_386750-22-7::Desvenlafaxine::NSC_6918664::O-Desmethylvenlafaxine::US9944618, Compound ID No. 181
SMILES CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1
InChI Key InChIKey=KYYIDSXMWOZKMP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 86748
Affinity DataKi: 4.10nMAssay Description:SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataIC50: 180nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human SERT expressed in CHO cells assessed as reduction of [3H]-5-HT re-uptake preincubated for 10 mins followed by [3H]-5-HT addition ...More data for this Ligand-Target Pair